The Coronavirus (COVID-19) Infection Survey (CIS) is run across the whole of the UK and aims to estimate:
- how many people have the infection over a given time (positivity);
- how many new cases occur over a given period (incidence); and
- how many people have antibodies to COVID-19.
The survey helps track the extent of infection and transmission of COVID-19 among people in private residences, referred to as the community population.
Due to some differences between laboratories’ recording of results, which required further quality assurance, we were unable to produce last week’s publication. As a result there are no official estimates available for the week ending 9 January 2021.
Proportion of people in Wales who had COVID-19
This equates to around 1 in 70 individuals (95% credible interval: 1 in 85 to 1 in 60), or an estimated 44,000 people in total (credible interval: 36,000 to 52,800).
The positivity rate has levelled off in the most recent week, after falling from the peak seen shortly before Christmas.
Because of the lag between people acquiring COVID-19 and testing positive, it is likely that any impact of the Christmas and new year period on rates testing positive will not be fully evident until the second week of January.
Since the estimates are based on a relatively low number of positive tests, there is some uncertainty and the results should be interpreted with caution.
Analysis of the new UK variant and other variants of the coronavirus indicates that the most recent decrease in Wales was driven by other variants. Cases compatible with the new variant appear to have increased in recent weeks.
Please note that there is a greater lag in data from the infection survey than from other sources such as Public Health Wales.
Antibodies (updated monthly)
As part of the survey we measure the presence of antibodies to understand who has had COVID-19 in the past. Updates to antibodies estimates are provided on a monthly basis.
One way the body fights infections like COVID-19 is by producing small particles in the blood called antibodies. It takes between two and three weeks for the body to make enough antibodies to fight the infection. The length of time antibodies remain at detectable levels in the blood is not fully known. It is also not yet known how having detectable antibodies, now or at some time in the past, affects the chance of getting COVID-19 again.
In December, 9.8% (95% confidence interval: 6.9% to 13.3%) of people aged 16 and over tested positive for antibodies to the coronavirus (COVID-19). The estimate is weighted to be representative of the overall population, and equates to around 1 in 10 people (95% confidence interval: 1 in 14 to 1 in 8), or around 247,000 individuals in total (95% confidence interval: 175,000 to 337,000).
Chart 3 gives monthly estimates from July (when antibody estimates were first available for Wales). Though there is uncertainty with the estimates, it does appear that antibody rates have increased in recent months. Antibody levels in the blood can decline over time, meaning that some people who have previously had COVID-19 may subsequently test negative for antibodies. For this reason, these figures should be regarded as estimates of monthly antibodies prevalence, not cumulative exposure.
Estimates for the countries of the UK
At the midpoint of the most recent week (10 to 16 January 2021) the highest estimated percentage of the community population with COVID-19 among the nations of the UK was in England (1.88%).
There is some uncertainty around the individual point estimates for the nations. Estimates for the last few days of the series, shown as dashed lines in the chart below, have more uncertainty.
The lines represent the modelled trend based on the latest data. Estimates for the last few days of the series, shown as dashed lines in the chart, have more uncertainty.
(95% Confidence Interval)
(1.18 to 1.74)
|1 in 70 people
(1 in 85 to 1 in 60)
(36,000 to 52,800)
(1.80 to 1.96)
|1 in 55 people
(1 in 55 to 1 in 50)
(978,900 to 1,070,000)
(0.84 to 1.15)
|1 in 100 people
(1 in 120 to 1 in 85)
(44,400 to 60,800)
(1.25 to 1.99)
|1 in 60 people
(1 in 80 to 1 in 50)
(23,000 to 36,500)
Source: Coronavirus (COVID-19) Infection Survey, ONS
This survey covers people living in private households only and this is referred to as the community population. Residents in hospitals, care homes and/or other institutional settings are excluded.
A confidence interval gives an indication of the degree of uncertainty of an estimate, showing the precision of a sample estimate. The 95% confidence intervals are calculated so that if we repeated the study many times, 95% of the time the true unknown value would lie between the lower and upper confidence limits. A wider interval indicates more uncertainty in the estimate. Overlapping confidence intervals indicate that there may not be a true difference between two estimates.
A credible interval gives an indication of the uncertainty of an estimate from data analysis. 95% credible intervals are calculated so that there is a 95% probability of the true value lying in the interval.
The number of new infections over a period of time.
Estimates of positivity from this survey are based on statistical modelling of the underlying data. The model smooths the series to understand the trend and is revised each week to incorporate new test results.
The headline point estimates are based on the modelled trend and are reflect the most representative reference point for the given week.
The estimated proportion of people who test positive for coronavirus (COVID-19) at a point in time, with or without symptoms, based on nose and throat swabs.
Quality and methodology information
The results of the survey are based on self-administered nose and throat swabs provided by participants to the study. A subgroup of participants also provide blood test, taken by trained field staff.
As well as looking at overall incidence, positivity and antibody level, the survey will be used to examine the characteristics of those testing positive for COVID-19 and the extent to which those infected experience symptoms. The results are for private households only and do not apply to those in hospitals, care homes or other institutional settings. This is referred to as the community population.
The survey covers all the countries of the UK, enabling estimates to be calculated for each country individually, and in time the UK as a whole. Fieldwork started first in England on 26 April meaning there is more cumulative data available for England enabling more detailed analysis at present. Fieldwork began in Wales on 29 June 2020 followed by Northern Ireland on 26 July and Scotland on 21 September.
The sample for Wales is not yet large enough to support more detailed analysis than is provided here (headline figures for positivity and antibodies). Fieldwork has been scaled up, with the intention of delivering approximately 9,000 participants per fortnight. Currently, the expectation is that this will be reached by mid-March. Sample increases will enable more detailed analysis, which may include incidence (the number of new infections over a period of time) and analysis of the characteristics of people testing positive. The type of analysis that is possible will also depend on the underlying prevalence of the virus, with higher infection rates enabling more analysis and vice versa.
It is important to note that there is a significant degree of uncertainty with the estimates. This is because, despite a large sample of participants, the number of positive cases identified is small. Estimates are provided with 95% credible or confidence intervals to indicate the range within which we may be confident the true figure lies.
The modelled estimates are carried out afresh each week using the previous 6 weeks’ data. The model works by smoothing the series to understand the trend and is revised each week to incorporate new test results. This means that the latest estimate for an earlier period may be different to the official estimate that was produced at the time. Chart 1 shows the latest modelled trend and the official (point) estimates that were published at the time.
The Office for National Statistics (ONS) publishes weekly statistical bulletins and references tables and periodic statistical articles which include results for England, Wales, Northern Ireland and Scotland as they become available. The estimates for Northern Ireland and Scotland are published by the respective administrations, as we do here for Wales.
Well-being of Future Generations Act (WFG)
The Well-being of Future Generations Act 2015 is about improving the social, economic, environmental and cultural well-being of Wales. The Act puts in place seven well-being goals for Wales. These are for a more equal, prosperous, resilient, healthier and globally responsible Wales, with cohesive communities and a vibrant culture and thriving Welsh language. Under section (10)(1) of the Act, the Welsh Ministers must (a) publish indicators (“national indicators”) that must be applied for the purpose of measuring progress towards the achievement of the Well-being goals, and (b) lay a copy of the national indicators before the National Assembly. The 46 national indicators were laid in March 2016.
Information on the indicators, along with narratives for each of the well-being goals and associated technical information is available in the Well-being of Wales report.
Further information on the Well-being of Future Generations (Wales) Act 2015.
The statistics included in this release could also provide supporting narrative to the national indicators and be used by public services boards in relation to their local well-being assessments and local well-being plans.